George Ford will play at flyhalf for England as they vie to claim the second Test.
England coach Eddie Jones has opted against picking Luther Burrell at inside centre, after pulling him in 29 minutes into the opening Test, in favour of George Ford and Owen Farrell at 10-12.
Farrell will line up at inside centre, with the only other change to the starting side being wing Jack Nowell coming off the bench, with Burrell out of the 23 altogether.
Speedster Marland Yarde has been left out of the 23 altogether, despite scoring a try in last week's 39-28 win over the Wallabies.
Jones has kept his front row intact and also maintained the selection of versatile youngster Maro Itoje in the locks.
Backrowers Chris Robshae, James Haskell and Billy Vunipola will also reignite their combination in the second Test, after eking out an advantage in the breakdown last week.
England team to face Wallabies on June 18 at AAMI Park
1. Mako Vunipola
2. Dylan Hartley
3. Dan Cole
4. Maro Itoje
5. George Kruis
6. Chris Robshaw
7. James Haskell
8. Billy Vunipola
9. Ben Youngs
10. George Ford
11. Jack Nowell
12. Owen Farrell
13. Jonathan Joseph
14. Anthony Watson
15. Mike Brown
Reserves
16. Jamie George
17. Matt Mullan
18. Paul Hill
19. Joe Launchbury
20. Courtney Lawes
21. Jack Clifford
22. Danny Care
23. Elliot Daly