Reece Hodge will start at inside centre for the Rebels, shaking off a hamstring injury to place the Bulls.
As expected, Michael Ruru has been handed the halfback spot in Will Genia's absence, with Junior Wallabies scrumhalf Harrison Goddard on the bench.
Billy Meakes drops back to the bench with Hodge's comeback, while Angus Cottrell and Matt Philip have been promoted to the starting side, after playing off the bench against the Jaguares.
Flyhalf Jack Debreczeni will play his 50th Super Rugby and Rebels match in the clash.
Rebels coach Dave Wessels said the match would be a big test for the Rebels, who have never won in South Africa.
"The Rebels have never won in South Africa, but to change that we’re going to have to play well against a very good Bulls team,” Wessels said.
“It’s exciting for guys like Michael (Ruru) and Harrison (Goddard); they have a great opportunity to impose themselves on the Super Rugby competition.
“The Bulls have played very well in the last few weeks and they’re obviously well-coached. We know that we’re going to have to be at our best.”
The Bulls host the Rebels on Saturday in Pretoria, kicking off at 3:05pm local, 11:05pm AEST, LIVE on FOX SPORTS.
TEAM
IN: Reece Hodge, Harrison Goddard, Fereti Saaga, Angus Cottrell
OUT: Will Genia, Ben Daley, Colby Faingaa, Lopeti Timani
Rebels to face the Bulls
1. Tetera Faulkner
2. Anaru Rangi
3. Sam Talakai
4. Matt Philip
5. Adam Coleman (C)
6. Ross Haylett-Petty
7. Angus Cottrell
8. Amanaki Mafi
9. Michael Ruru
10. Jack Debreczeni
11. Marika Koroibete
12. Reece Hodge
13. Tom English
14. Jack Maddocks
15. Dane Haylett-Petty
Reserves
16. Jordan Uelese
17. Fereti Sa’aga
18. Jermaine Ainsley
19. Geoff Parling
20. Richard Hardwick
21. Harrison Goddard
22. Billy Meakes
23. Sefa Naivalu
