Rugby World Cup winning lock RG Snyman has been named in the Springboks' squad for three Tests next month, South Africa Rugby announced on Tuesday.
Snyman missed the summer's Rugby Championship success with a foot injury but has scored two tries in three games this season for new side Leinster.
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The 29-year-old is joined in the set-up by utility back Damian Willemse, centre Andre Esterhuizen and fellow second-row Franco Mostert, who were also sidelined for the mid-year campaign.
Fly-half Sacha Feinberg-Mngomezulu, locks Salmaan Moerat and Lood de Jager as well as prop Steven Kitshoff are missing however with fitness issues.
“There's no doubt that there are several unlucky players who could easily have made the touring squad, but unfortunately we could only select 34 players," South Africa head coach Rassie Erasmus said.
"It's also great to have RG, Franco, Andre, and Damian back in the mix after recovering from their injuries, and we are excited to see what impact they have on the field, especially after their disappointment of missing out on the Rugby Championship.
"Damian, Andre and RG all returned to action in the Vodacom United Rugby Championship and have made a strong statement with their performances, and we all know what a work horse Franco is and the quality that he adds to the team, so there’s no doubt they’ll want to make their presence felt against quality opposition," he added.
The Springboks face Scotland on November 10, England six days later and then Wales on November 23.
Erasmus' side head north having lost just two games this season, against Ireland and Argentina, a year on from lifting the World Cup last October.
"We are under no illusions about the quality of the opposition we will face, and we have experienced first-hand how their home crowds lift them, much like our passionate supporters, so we know what it will take to be successful over there," he said.
"Fortunately, we have a squad that believes in themselves and their abilities, and that will be vital as we enter these matches.
"Obviously we'll take confidence from winning the Rugby Championship, but the reality is that's now history, and there’s no doubt that will motivate the opposition even more to make a strong statement against us," he added.
Backs (16): Kurt-Lee Arendse, Aphelele Fassi, Cheslin Kolbe, Willie le Roux, Makazole Mapimpi, Canan Moodie, Damian Willemse; Lukhanyo Am, Damian de Allende, Andre Esterhuizen, Jesse Kriel; Manie Libbok, Handre Pollard; Jaden Hendrikse, Cobus Reinach, Grant Williams
Forwards (18): Jan-Hendrik Wessels, Pieter-Steph du Toit, Siya Kolisi (capt), Elrigh Louw, Kwagga Smith, Marco van Staden, Jasper Wiese; Eben Etzebeth, Franco Mostert, Ruan Nortje, RG Snyman, Malcolm Marx, Bongi Mbonambi, Thomas du Toit, Vincent Koch, Frans Malherbe, Ox Nche, Gerhard Steenekamp