The Brumbies and Crusaders have opted to rest a number of key players after their brutal finals ahead of Round One.
Coming off a Super Rugby Aotearoa win, Mitch Drummond and Will Jordan have both been rested, with regular captain Scott Barrett and Seve Reece reverting to the bench.
Watch every minute of Super Rugby Trans-Tasman on Stan Sport. Start your Free Sport Trial Now
This allows centurion and hooker Cody Taylor to take the captaincy, becoming the 21st player in club history to reach triple figures.
"Codie is not only a world-class player, he's an empathetic leader who knows how to get the best out of those around him and sets high standards in our environment," coach Scott Robertson said.
"We're really excited for Codie and his family, it's a special milestone for a special player."
Mitch Dunshea comes into the locksa alongside Sam Whitelock, whilst Bryn Hall has been named to start this match and Ereatara Enari will have an opportunity from the bench in place of Drummond.
Sione Havili Talitui (concussion) has also been ruled out, replaced by Brendon O'Connor.
As for the Brumbies, coach Dan McKellar has been forced into a number of changes as a result of injury, led by halfback Nic White.
White, who has played in every game in Super Rugby AU, has been replaced by Ryan Loergan, with Issak Fines-Leleiwasa returning to the bench.
The Wallabies halfback is joined on the sidelines by Caderyn Neville and Andy Muirhead after their breakout 2021 campaigns.
Nick Frost shifts to lock in Neville's place, allowing new recruit Henry Stowers to earn his starting debut for the club whilst Solomone Kata returns to the starting side.
Folau Fainga'a returns to the starting side in his 50th Super Rugby game.
CRUSADERS (1-15): George Bower, Cody Taylor (c), Michael Alaalatoa, Mitchell Dunshea, Sam Whitelock, Ethan Blackadder, Tom Sanders, Cullen Grace, Bryn Hall, Richie Mo'unga, Leciester Fainga'anuku, David Havili, Braydon Ennor, Manasa Mataele George Bridge
Reserves: Brodie McAlister, Tamati Williams, Oliver Jager, Scott Barrett, Brendon O'Connor, Ereatara Enari, Fergus Blake, Seve Reece
INs: Brendon O'Connor, Ereatara Enari, Fergus Blake, Manasa Mataele
OUTs: Sione Havili Talitui, Mitchell Drummond, Will Jordan, Seve Reece,
BRUMBIES (1-15): Scott Sio, Folau Fainga'a, Allan Alaalatoa (c), Darcy Swain, Nick Frost, Henry Stowers, Rory Scott, Rob Valetini, Ryan Lonergan, Noah Lolesio, Tom Wright, Irae Simone, Len Ikitau, Solomone Kata, Tom Banks
Reserves: Lachlan Lonergan, Harry Lloyd, Tom Ross, Tom Hooper*, Luke Reimer, Issak Fines-Leleiwasa, Reesjan Pasitoa, Mack Hansen
INs: Tom Hooper, Issak Fines-Leleiwasa, Solomone Kata
OUTs: Caderyn Neville, Nic White, Andy Muirhead
