The Wallabies are set to elevate Taniela Tupou to the starting side as they prepare to face France in Paris.
This comes as Allan Alaalatoa has been ruled out after suffering a concussion during last week's 16-15 win over Scotland.
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Alaalatoa was replaced at half-time after presenting with concussion symptoms, with the 12-day turnaround ruling him out.
It is the Brumbies skipper's second concussion in four months, ruled out of the final Test of the England series.
The Wallabies will be looking for back-to-back wins for the first time in 2022 as they face the reigning Six Nations champions on Sunday morning (AEDT).
France have built a ten-game winning streak since they last played the Wallabies, with Dave Rennie's men surviving three close games to take a 2-1 series victory.
However, the second-ranked Les Bleus have a vastly different team than 16 months ago, headlined by the inclusion of Antoine Dupont, Charles Ollivon and Romain Ntamack.
Jed Holloway is one of several new faces in the Wallabies squad since that series, watching the intense battles 'with his feet up and relaxing' in the USA before joining the Waratahs.
He believes past results will mean nothing as they look to build momentum for the rest of the tour.
“We haven’t really talked about the French series from last year,” Holloway remarked.
“They said they brought out their ‘B’ side and fair enough, Dupont was playing. To be fair, me, Langi and a few boys here didn’t even play in that series.
“We can’t really go back and take anything out of it. We’re playing France in France which is the number two side in the world which is going to be a hell of a spectacle but that’s motivation enough to really build through the week and fire up.”
The Wallabies will confirm their side late Thursday evening, with lock Will Skelton available for selection after joining the camp in Saint-Etienne